Superoxide dismutase as an inhibitor of reactions of semiquinone radicals

Superoxide dismutase Superoxide dismutase

Mitochondrial complex I deficiency leads to increased production of superoxide radicals and induction of superoxide dismutase.

Mitochondria were isolated from skin fibroblast cultures derived from healthy individuals (controls) and from a group patients with complex I (NADH-CoQ reductase) deficiency of the mitochondrial respiratory chain. The complex I deficient patients included those with fatal infantile lactic acidosis (FILA), cardiomyopathy with cataracts (CC), hepatopathy with tubulopathy (HT), Leigh's disease (LD...

nano-rods zno as an efficient catalyst for the synthesis of chromene phosphonates, direct amidation and formylation of amines

چکیده ندارد.

On the action of diethyldithiocarbamate as inhibitor of copper-zinc superoxide dismutase.

The rate constants of the reactions between pulse radiolytically produced superoxide radicals and the Cu(II) chelate of diethyldithiocarbamate were determined at pH 7.0. It was found that diethyldithiocarbamate forms a copper complex, which as no dismutating activity. The removal of the protein bound copper in superoxide dismutase by diethyldithiocarbamate yields the same effect as coordination...

The ABC’s of the Reactions between Nitric Oxide, Superoxide, Peroxynitrite and Superoxide Dismutase

The interplay between nitric oxide and superoxide to form peroxynitrite is a major biological process that competes in a remarkably subtle fashion with superoxide dismutase in vivo. The complex interactions between superoxide, nitric oxide reveals some extraordinary features about the difficulties of effectively scavenging of superoxide in a biological system. The discovery of dominant mutation...